DEPARTAMENTO DE FARMACOLOGÍA
FACULTAD DE MEDICINA, UNAM.

Responsable: Dr. JUAN ARCADIO MOLINA GUARNEROS

PROFESOR TITULAR “A” T. C

molina_ja2007@yahoo.com.mx

Académicos.

M. en C. Maribel Soto Núñez

inmunofarmacologia@yahoo.com.mx

Técnico Académico Asociado “A” T. C.

Alumnos:

.

Q.F.B. Patricia Cuautle Rodríguez

Maestría en Ciencias Biológicas (Biología Experimental)

Posgrado en Ciencias Biológicas, UNAM.

matlazihuatzin@yahoo.com.mx

LINEAS DE INVESTIGACIÓN

1.-MODULACIÓN FARMACOLÓGICA IN VIVO E IN VITRO DE LA RESPUESTA INMUNE MURINA:

ESTUDIO IN VITRO DE LA ACCION DE LA 7-HIDROXICUMARINA E IN VIVO DE LA CUMARINA, EN LA INDUCCION DE LA SECRECION DE INTERLEUCINA-3 EN EL RATON.

2.-DESARROLLO DE MEDICAMENTOS CON POTENCIAL TERAPÉUTICO EN HUMANOS.

ESTUDIO IN VITRO DEL MECANISMO INDUCTOR DE LA APOPTOSIS DE LA 7-HIDROXICUMARINA EN LÍNEAS DE ADENOCARCINOMA PULMONAR HUMANO.

PUBLICACIONES ULTIMOS CINCO AÑOS

ACTIVATION OF PROTEIN KINASE A STIMULATES THE PROGESTERONE-INDUCED CALCIUM INFLUX IN HUMAN SPERM EXPOSED TO THE PHOSPHODIESTERASE INHIBITOR PAPAVERINE. VÍCTOR TORRES-FLORES, YADIRA LIBERTAD HERNÁNDEZ-RUEDA, PALOMA DEL CARMEN NERI-VIDAURRI, FRANCISCO JIMÉNEZ-TREJO, VÍCTOR CALDERÓN-SALINAS, JUAN A. MOLINA-GUARNEROS, MARCO T. GONZÁLEZ-MARTÍNEZ. JOURNAL OF ANDROLOGY (ACEPTADO), 2008.

MECHANISMS OF ANTITUMOR EFFECTS OF SIMPLE COUMARINS IN MURINE MELANOMA AND HUMAN NON-SMALL CELL LUNG CARCINOMA CELL LINES. JOSE SULLIVAN LOPEZ-GONZALEZ, HERIBERTO PRADO-GARCIA, JUAN A. MOLINA-GUARNEROS, NICANDRO MENDOZA-PATIÑO, PATRICIA ROSAS-MEDINA, JUAN J. MANDOKI. IN COUMARIN ANTICOAGULANT RESEARCH PROGRESS, JOSEPH P. EDARDES, EDITOR. NOVA SCIENCE PUBLISHERS, INC. NEW YORK, U.S.A., 2008. pp.99-112  ISBN: 978-1-1-60021-990-0.

HUMAN CEMENTUM PROTEIN 1 INDUCES EXPRESSION OF BONE AND CEMENTUM PROTEINS BY HUMAN GINGIVAL FIBROBLASTS. BRUNO CARMONA-RODRIGUEZ, MARCO ANTONIO ALVAREZ-PEREZ, A. SAMPATH NARAYANAN, MARGARITA ZEICHENER-DAVID, JOSE REYES- GASGA, JUAN MOLINA-GUARNEROS, ANA LILIA GARCIA-HERNANDEZ, JOSE LUIS SUAREZ-FRANCO, IVET GIL-CHAVARRIA, EDUARDO VILLAREAL-RAMIREZ, HIGINIO ARZATE. BIOCHEMICAL AND BIOPHYSICAL COMMUNICATIONS (2007). Jul 6;358(3):763-9.

RECOVERY AFTER A TRAUMATIC BRAIN INJURY DEPENDS ON DIURNAL VARIATIONS. EFFECTS OF CYSTATIN C. MARTINEZ-VARGAS M, GONZALEZ-RIVERA R, SOTO-NUÑEZ M, CISNEROS-MARTINEZ M, HUERTA-SAQUERO A, MORALES-GOMEZ J, MOLINA-GUARNEROS J, NAVARRO-ANGULO L. NEUROSCIENCE LETTERS (2006); 400:21-24.

MOLECULAR ASSOCIATION OF LECTIN AND -GLUCOSIDASE IN CORN COLEOPTILE. JUAN MOLINA, ABRAHAM LANDA, GONZALO BAUTISTA, MARGARITO MARTINEZ, FELIX CORDOBA. BIOCHIMICA ET BIOPHYSICA ACTA GENERAL SUBJECTS (2004) 1674: 3; 299-304

HORMONE MULTIFUNCTIONALITIES: ENDOCRINE SIGNALING COMMAND AND CONTROL. JUAN JOSE MANDOKI, NICANDRO MENDOZA-PATIÑO, JUAN A. MOLINA-GUARNEROS, FAUSTO ALEJANDRO JIMENEZ-OROZCO, MARCO ANTONIO VELASCO-VELAZQUEZ, MARIA JUANA GARCIA-MONDRAGON. PROGRESS IN BIOPHYSICS AND MOLECULAR BIOLOGY. (2004) 43, 275-283.

APOPTOSIS AND CELL CYCLE DISTURBANCES INDUCED BY COUMARIN AND 7-HYDROXYCOUMARIN ON HUMAN LUNG CARCINOMA CELL LINES. JOSE SULLIVAN LÓPEZ-GONZÁLEZ, HERIBERTO PRADO-GARCÍA, DOLORES AGUILAR-CÁZARES, JUAN A. MOLINA-GUARNEROS, JORGE MORALES-FUENTES, JUAN JOSE MANDOKI. LUNG CANCER (2004) 43, 275-283.

Human cementum protein 1 induces expression of bone and cementum proteins by human gingival fibroblasts (pdf)

Recovery after a traumatic brain injury dependents on diurnal variations, Effect of cystatin C (pdf)

Molecular association of lectin and b-glucosidase in corn coleoptile (pdf)

Hormone multifunctionalities: a theory of endocrine signaling, command and control (pdf)

Apoptosis and cell cycle disturbances induced by coumarin and 7-hydroxycoumarin on human lung carcinoma cell lines (pdf)